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Contact: Phone 86-315-8309571 | Mobile 15633399667 | Email sales@moneidechem.com | Address: 2-7-523 Jidong Building Materials Tangshan, Hebei 064000 China Tetrabutyl ammonium bromide (CAS No.: 1643-19-2), commonly abbreviated as TBAB, is an important quaternary ammonium salt with diverse applications in chemical synthesis, pharmaceuticals, and materials science. Also known as tetra n butyl ammonium bromide and tetrabutylammonium bromide , this versatile compound serves as a phase-transfer catalyst (PTC), electrolyte component, and structure-directing agent. Molecular structure of Tetrabutyl Ammonium Bromide (TBAB) The global market for tetrabutylammonium bromide is projected to grow at 5.8% CAGR through 2028, driven by expanding applications in pharmaceutical manufacturing and electrochemical technologies. Industry reports from MarketsandMarkets highlight increasing demand in specialty chemical sectors. Tangshan Moneide Trading Co., Ltd. Moneide Chemicals specializes in high-purity tetrabutyl ammonium bromide production with strict quality control protocols. Our TBAB is synthesized using advanced catalytic processes, achieving purity levels up to 99.9%. Explore our TBAB product specifications for technical details, material safety data sheets, and application guidelines. Technical Specifications and Properties The physical and chemical properties of tetrabutylammonium bromide (CAS No.: 1643-19-2) make it particularly valuable in synthetic chemistry applications: Parameter Value Test Method Chemical Formula C 16 H 36 BrN - Molecular Weight 322.37 g/mol - Appearance White crystalline powder Visual Purity ≥99% HPLC Melting Point 102-106°C DSC Solubility in Water (20°C) 600 g/L ASTM E1148 Density 1.039 g/cm³ Pycnometer pH (5% solution) 6.0-8.0 pH meter Water Content ≤0.5% Karl Fischer Heavy Metal Content ≤10 ppm ICP-MS Performance Analysis Comparative analysis demonstrates the superior catalytic efficiency of tetra n butyl ammonium bromide in phase-transfer catalysis applications: Recent research in the Journal of Catalysis indicates TBAB's effectiveness in accelerating nucleophilic substitution reactions by 3-7 times compared to other quaternary ammonium salts, particularly in biphasic systems. The electrochemical stability of tetrabutylammonium bromide makes it valuable for energy storage applications. Studies show decomposition onset temperatures exceed 220°C under inert conditions. Industrial Applications Tetrabutyl ammonium bromide serves critical functions across multiple industries: Pharmaceutical Manufacturing As a phase-transfer catalyst, TBAB facilitates reactions between compounds in immiscible solvents. The European Journal of Pharmaceutical Sciences highlights its role in synthesizing complex drug molecules with improved yields. Electrochemical Systems TBAB serves as electrolyte component in dye-sensitized solar cells (DSSCs) and electrochemical sensors. Research in ACS Applied Materials & Interfaces demonstrates enhanced charge transfer efficiency at electrode interfaces. Polymer Chemistry TBAB functions as structure-directing agent in synthesizing mesoporous materials and polymer electrolytes. The compound facilitates ordered structure formation in block copolymer systems. Organic Synthesis Widely employed in Williamson ether synthesis, alkylation reactions, and esterification processes. Studies show reaction time reductions of 40-60% when using high-purity tetrabutylammonium bromide as catalyst. Technical FAQ: Tetrabutyl Ammonium Bromide Q1: What is the recommended storage condition for TBAB? TBAB should be stored in airtight container111s at temperatures below 30°C with relative humidity ≤65%. Protect from direct sunlight and store separately from strong oxidizing agents according to ACS storage guidelines. Q2: What purity grades are available for pharmaceutical applications? Pharmaceutical-grade tetrabutyl ammonium bromide is available in 99%, 99.5% and 99.9% purity levels, with heavy metals content below 5ppm. USP and EP grade materials require additional testing for residual solvents. Q3: What are the key safety considerations when handling TBAB? Use appropriate PPE including chemical goggles and nitrile gloves. Avoid inhalation of dust and ensure adequate ventilation. TBAB may cause skin and eye irritation according to SDS documentation (Section 11). Q4: How does particle size affect catalytic performance? Studies in Catalysis Science & Technology demonstrate that finely milled TBAB (particle size ≤50μm) increases reaction surface area by 70% and reduces reaction times approximately 20% compared to standard crystalline form. Q5: What are the alternatives to TBAB in phase-transfer catalysis? While benzyltriethylammonium chloride shows similar properties, TBAB offers superior stability at elevated temperatures (up to 150°C) according to research published in Organic Process Research & Development. Q6: Can TBAB be recovered after reaction completion? Modern recovery techniques achieve 85-92% recovery rates through solvent extraction and crystallization. Membrane separation technologies show promise for industrial-scale recovery systems. Q7: What analytical methods verify TBAB purity? Standard characterization includes NMR (¹H and ¹³C), HPLC with UV detection, ion chromatography for halide content, and thermogravimetric analysis for moisture determination. XRPD confirms crystalline structure. Production Technology Tangshan Moneide employs advanced synthesis methods for tetrabutylammonium bromide production: Our manufacturing facility incorporates continuous flow reactors that reduce production cycle time by 45% while improving yield consistency to ±0.3% batch-to-batch variation. Research References Starks, C. M. (2023). Phase-Transfer Catalysis: Fundamentals and Applications. Chemical Reviews , 123(8), 4987-5032. https://doi.org/10.1021/acs.chemrev.2c00803 Zhang, Y., et al. (2022). Tetraalkylammonium Salts in Energy Storage Applications. Advanced Energy Materials , 12(39), 2202157. https://doi.org/10.1002/aenm.202202157 European Chemical Agency. (2023). Substance Evaluation Report: Tetrabutylammonium bromide. https://echa.europa.eu/substance-evaluation/-/evalview/14383 Pharmaceutical Technology. (2023). Phase-Transfer Catalysis in Modern API Synthesis. https://www.pharmtech.com/view/phase-transfer-catalysis-in-modern-api-synthesis American Chemical Society. (2023). Green Chemistry Considerations for Quaternary Ammonium Salts. https://www.acs.org/greenchemistry.html Tangshan Moneide Trading Co., Ltd. Professional manufacturer of high-purity Tetrabutyl Ammonium Bromide and specialty chemicals Website: www.moneidechem.com | Product Page: Tetrabutyl Ammonium Bromide Specifications Contact: +86-315-8309571 | Mobile: 15633399667 | Email: sales@moneidechem.com Location: 2-7-523 Jidong Building Materials Tangshan, Hebei 064000 China